Representative MITE-like transposition units
A MITE-like transposition unit is bracketed by IRL/IRR with short DRs at each extremity and carries no transposase genes, similar to MITEs 1. In contrast to MITEs that harbor no accessory genes, this unit contains one or more accessory genes such as the antimicrobial resistance genes. This unit is mobilized by recognizing its IRL/IRR by a transposase acting in trans, displaying a mobilization mechanism similar to MITEs.
Table 1|List of representative MITE-like transposition units
| Category | Sub-category | Designation | Accession number | Synonym | Resistance genes | DR | FASTA sequence | Gene list | GBK-annotation | SQN-annotation | Manual annotation | Gene organization |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MITE-like transposition unit | Tn6893 | MH674200 | chrB, and mcr-5.1 | AATTA |  |
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References
1. Kieffer N, Nordmann P, Millemann Y et al. Functional characterization of a miniature inverted transposable element at the origin of mcr-5 gene acquisition in Escherichia coli. Antimicrob Agents Chemother 2019; 63.