Representative MITE-flanking transposition units
MITEs 1 are a group of non-autonomous transposable elements, and require other "helper" elements that encode transposases. MITEs have terminal IRL/IRR pairs and are flanked by short DRs. An MITE-flanking transposition unit typically has a structure of flanking an intact or incomplete genetic element (such as an integron 2) by two copies of MITE, with short DRs bracketed at both ends. Instead of each MITE moving separately, the MITE-flanking transposition unit transposes as one complete unit.
Table 1|List of representative MITE-flanking transposition units
| Category | Sub-category | Designation | Accession number | Synonym | Resistance genes | DR | FASTA sequence | Gene list | GBK-annotation | SQN-annotation | Manual annotation | Gene organization |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MITE-flanking transposition unit | Tn6508 | JX235356 | MITE-In796-MITE unit | aacA7, blaVIM-2, aacC1, qacEDl, and sul1 | TCAAT |  |
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References
1. Delihas N. Impact of small repeat sequences on bacterial genome evolution. Genome Biol Evol 2011; 3: 959-73.
2. Domingues S, Toleman MA, Nielsen KM et al. Identical miniature inverted repeat transposable elements flank class 1 integrons in clinical isolates of Acinetobacter spp. J Clin Microbiol 2013; 51: 2382-4.