Representative IS-based transposition units

An IS-based transposition unit typically harbors an IS element together with the captured genes or genetic elements at its downstream end. Instead of the single IS element moving, the IS-based transposition unit is mobilized as one complete unit, which is bordered by IRL/IRR.

Table 1|List of representative IS-based transposition units

CategorySub-categoryDesignationAccession numberSynonymResistance genesDRFASTA sequenceGene listGBK-annotationSQN-annotationManual annotationGene organization
IS-based transposition unit IS1247-based Tn6884 KY978628 IS1247aac3arr7 transposition unit aacC3, and arr7
IS-based transposition unit ISApl1-based Tn6506 KP347127 ISApl1mcr-1 transposition unit mcr-1 GA
IS-based transposition unit ISEcp1-based Tn2012 EU523120 ISEcp1qnrB19 transposition unit qnrB19 ATCAA
IS-based transposition unit ISEcp1-based Tn2013 JN205800 ISEcp1blaOXA-181 transposition unit blaOXA-181 ATATA
IS-based transposition unit ISEcp1-based Tn6092 AY509004 ISEcp1blaCMY-2 transposition unit blaCMY-2, blc, and sugE GATAA
IS-based transposition unit ISEcp1-based Tn6502a KF914891 ISEcp1blaCTX-M-3orf477 transposition unit blaCTX-M-3
IS-based transposition unit ISEcp1-based Tn6503a KP987215 ISEcp1blaCTX-M-14–IS903D transposition unit blaCTX-M-14 TAACA
IS-based transposition unit ISEcp1-based Tn6503b EU195449 ISEcp1blaCTX-M-24–IS903D transposition unit blaCTX-M-24 TAACA
IS-based transposition unit ISEcp1-based Tn6503c CP028782 ISEcp1blaCTX-M-27–IS903D transposition unit blaCTX-M-27
IS-based transposition unit ISEcp1-based Tn6504 AB194779 ISEcp1rmtC transposition unit rmtC TTCAA
IS-based transposition unit ISEcp1-based Tn6538 KU160531 ISEcp1blaCMY-2 transposition unit blaCMY-2, blc, and sugE
IS-based transposition unit ISEcp1-based Tn6887 MG228427 ISEcp1blaACC-1 transposition unit blaACC-1 TCTTC
IS-based transposition unit ISEcp1-based Tn6888 KY073238 ISEcp1qnrE1 transposition unit qnrE1
IS-based transposition unit ISEnca1-based Tn6889 AY939911 ISEnca1aph(2')-le transposition unit aph(2')-le
IS-based transposition unit ISKpn23-based Tn6892 KP689347 ISKpn23blaBKC-1 transposition unit blaBKC-1
IS-based transposition unit ISPa17-based Tn6394 MF344578 ISPa17–In992 transposition unit aacA7, and blaIMP-1 ATGCA